CCS2000冷卻系統設計用于冷藏并保持的代謝籠樣品在或低于45華氏度(7攝氏度)。

產品由三部分組成：
1）15個MMC100小鼠代謝籠；
2）籠架；
3）冷卻裝置。
它是為我們的標準代謝籠和籠架而設計的，因此，它提供了所有hatteras產品相同的質量和功能保證。

使用要求:
盡管該系統是精心設計制作的，但是它的使用時很簡單的。安裝過程包括：將絕緣底座插入連接端口，將代謝籠放置到籠架上，給水槽中注水，和啟動系統。就是這樣。系統將自動開始制冷，以及維持與周圍溫度（室溫）30度左右的溫差。系統是可靠的和耐用的，不需要特殊的維護。

安裝開始于制冷單元，制冷單元安裝在籠架的底部，包含電子單元用來制冷和維持水的溫度。還包括水槽，用來實現水循環。另外，該單元還包括一個控制器用來顯示和控制溫度水平。

籠架系統是一個支撐設施，包含鉛管系統和制冷單元，作為代謝籠的連接點?；\架是鋁質的，帶有烤漆。3排水平結構，每個水平結構上帶有5個小孔用來安裝代謝籠。每一排的旁邊的背板上是連接的端口，用來連接代謝籠的絕緣底座到鉛管。制冷的絕緣底座為尿液樣本提供制冷?；\子由丙烯酸零部件和不銹鋼底板和獨特設計的不銹鋼收集漏斗組成?？梢允孢m的安全的連續24小時飼養一只小鼠，制冷的代謝籠提供和標準的代謝籠一樣的收集能力。

產品優勢:
冷卻尿液樣本將確保幾個用于研究的好處:
1 保持樣品的質量；
2 消除細菌繁殖；
3 維持一個穩定的pH值；
4 保持樣本的活性；
此外，制冷過程可保持溫暖環境氣候中的籠內環境冷卻，從而為老鼠提供更舒適的空氣。

產品優勢:
冷卻尿液樣本將確保幾個用于研究的好處:
1 保持樣品的質量；
2 消除細菌繁殖；
3 維持一個穩定的pH值；
4 保持樣本的活性；
此外，制冷過程可保持溫暖環境氣候中的籠內環境冷卻，從而為老鼠提供更舒適的空氣。

KynurenineInfusion Disrupts Normal Blood Pressure Circadian Rhythms

DebraL IrsikW.BollagC.Isales

Biology, Medicine

The FASEB Journal   1 May 2022

The data suggest that kynurenine treatment impacts renalfunction and may contribute to the development of CKD, a significant riskfactor for cardiovascular disease, even in the context of normotension.

Changes inOxygen Consumption and Metabolomic Profiles in the Kidney of Sprague‐Dawley Rat fed a High‐Salt Diet

S.ShimadaBrianR. HoffmannAndrewS. GreeneMingyuLiangR.DashA.Cowley

Medicine, Biology

The FASEB Journal  1May 2022

It is concluded that a high‐salt diet increases oxygenconsumption and alters the metabolomic profiles of the kidney.

Toward the InterdisciplinaryTheory and Research

O.Yanitsky

Creative Education  6 March 2020

The article represents some thoughts and considerationson an interdisciplinary theory and research based on the relevant scientificworks and the author’s personal and “big family” experience and…

Toward theInterdisciplinary Theory and Research

AixaHafsha  19 April 2020

The article represents some thoughts and considerationson an interdisciplinary theory and research based on the relevant scientificworks and the author’s personal and “big family” experience and… 

High Salt DietIncreases Renal Oxygen Consumption in Sprague‐Dawley Rats

S.ShimadaR.DashA.Cowley

The FASEB Journal  1May 2021

It appears that in normal SD rats, the increased tubular metabolic workassociated with a high salt diet is initially accommodated by increasedperfusion (RBF) and a gradual increase of O2 consumption while extractionremains unchanged for a two‐week period.

Chronic RenalArtery Insulin Infusion Decreases 24 hr/day Renal Blood Flow in Diabetic Rats

M.BrandsW.Bush   Medicine, Biology

The FASEB Journal  1May 2021

A chronic renal vasoconstrictor influence of insulinunder diabetic conditions is suggested, which suggests that the decrease ininsulin may contribute directly to the renal vasodilation that occurs in type 1diabetes.

M.CrostelliO.MazzaM.MarianiD.MascelloC.Iorio

International Orthopaedics 14 September 2018

Bracing is a viable treatment strategy in thoracic lumbarkyphosis and can obtain good clinical results at medium terms follow-up even ifkyPHosis deformity remains in radiographs, as even smallest devices availableare often too big.

Precise Controlof Target Temperature Using N6-Cyclohexyladenosine and Real-Time Control ofSurface Temperature.

B.LaughlinI.BaileyS.RiceZ.BaratiLoriK. BogrenK.Drew

Therapeutic Hypothermia and Temperature…1 June 2018

An intravenous delivery protocol for CHA at 0.25mg/(kg·h) that, when coupled with conductive cooling, achievesand maintains a prescribed and consistent target Tb between 32°Cand 34°C for 24 hours.

Physiologicalhyperinsulinemia caused by acute hyperglycemia minimizes renal sodium loss bydirect action on kidneys.

DebraL IrsikM.Brands

Medicine, Biology American Journal of Physiology.Regulatory…  23 May 2018

The hypothesis that meal-induced increases in plasmainsulin are a major component of normal sodium homeostasis, and that thisoccurs by direct action of insulin on the kidney is supported.

The normalincrease in insulin after a meal may be required to prevent postprandial renalsodium and volume losses.

DebraL IrsikB.Blazer-YostA.StaruschenkoM.Brands

Medicine, Biology

American Journal of Physiology. Regulatory…   1 June 2017

It is demonstrated that the normal increase incirculating insulin in response to hyperglycemia may be required to preventexcessive renal sodium and volume losses and suggested that insulin may be a physiologicalregulator of sodium balance.